Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22035590 | 0.78 | KDM1A (0.72) | KDM1ACYP11B2CYP11B1 | |
| SCHEMBL17375985 | 0.78 | KDM1A (1.00) | KDM1A | |
| SCHEMBL30790422 | 0.70 | CYP11B2 (0.47) | KDM1ACYP11B2CYP11B1 | |
| SCHEMBL25975389 | 0.70 | CYP11B2 (0.47) | KDM1ACYP11B2CYP11B1 | |
| SCHEMBL20459955 | 0.69 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL18297999 | 0.68 | CYP11B2 (0.67) | CYP11B2CYP11B1 | |
| SCHEMBL20459995 | 0.68 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL9151348 | 0.67 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| SCHEMBL22035587 | 0.67 | KDM1A (0.45) | KDM1ACYP11B2CYP11B1 | |
| SCHEMBL16771978 | 0.67 | TRPV4 (0.52) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160956-B1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2020-05-27 | — | — | EP | disclosed |