Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 14/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22041628 | 0.80 | GPR35 (0.47) | GPR35HPGDUSP2POLBALOX15 | |
| SCHEMBL22041626 | 0.79 | GPR35 (0.64) | GPR35HPGDUSP2POLBALOX15 | |
| SCHEMBL9319268 | 0.78 | ADORA3 (0.67) | GPR35HPGDPOLBHSD17B10CA12 | |
| SCHEMBL22041595 | 0.78 | GPR35 (0.47) | GPR35HPGDUSP2POLBALOX15 | |
| SCHEMBL12038474 | 0.78 | GPR35 (0.50) | GPR35HPGDUSP2POLBALOX15 | |
| SCHEMBL22041606 | 0.77 | GPR35 (0.71) | GPR35HPGDUSP2POLBALOX15 | |
| SCHEMBL11347549 | 0.71 | CA12 (0.77) | GPR35HPGDPOLBHSD17B10MAOB | |
| SCHEMBL9068668 | 0.71 | GPR35 (1.00) | GPR35HPGDUSP2POLBALOX15 | |
| SCHEMBL1096938 | 0.70 | KDM4E (0.45) | HPGDUSP2CASP1HSD17B10ALDH1A1 | |
| SCHEMBL17942936 | 0.70 | KDM4E (0.42) | GPR35HPGDPOLBALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285790-A | 3-carboxycoumarin derivative capable of serving as GPR35 agonist, preparation method and application | 泰州医药城国科化物生物医药科技有限公司 | 2020-06-16 | — | — | CN | claimed |
| WO-2020114290-A1 | 3-CARBOXYL COUMARIN DERIVATIVE CAPABLE OF BEING USED AS A GPR35 AGONIST, PREPARATION METHOD, AND APPLICATION | 泰州医药城国科化物生物医药科技有限公司 | 2020-06-11 | — | — | WO | claimed |
| CN-111285790-A | 3-carboxycoumarin derivative capable of serving as GPR35 agonist, preparation method and application | 泰州医药城国科化物生物医药科技有限公司 | 2020-06-16 | — | — | CN | disclosed |
| WO-2020114290-A1 | 3-CARBOXYL COUMARIN DERIVATIVE CAPABLE OF BEING USED AS A GPR35 AGONIST, PREPARATION METHOD, AND APPLICATION | 泰州医药城国科化物生物医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |