SCHEMBL9068668

SCHEMBL9068668

O=C(O)c1cc2cc(Cl)cc(Cl)c2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 8/20 1.00
USP2 O75604 1/20 1.00
POLB P06746 1/20 1.00
HPGD P15428 1/20 1.00
ALOX15 P16050 1/20 1.00
ALOX12 P18054 1/20 1.00
CASP1 P29466 1/20 1.00
CASP7 P55210 1/20 1.00
HSD17B10 Q99714 1/20 1.00
F12 P00748 3/20 0.64
ALDH1A1 P00352 3/20 0.62
KDM4E B2RXH2 2/20 0.62
MAPT P10636 1/20 0.62
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
MAOB P27338 2/20 0.54
MAOA P21397 2/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1367802 0.88 GPR35 (0.79) GPR35USP2POLBHPGDALOX15
SCHEMBL30110303 0.87 GPR35 (0.77) GPR35USP2POLBHPGDALOX15
SCHEMBL30110275 0.85 GPR35 (0.74) GPR35USP2POLBHPGDALOX15
SCHEMBL17037290 0.85 GPR35 (0.74) GPR35USP2POLBHPGDALOX15
SCHEMBL52311 0.82 HPGD (0.69) GPR35USP2POLBHPGDALOX15
SCHEMBL18306420 0.79 MAOA (0.71) GPR35USP2POLBHPGDALOX15
SCHEMBL11494991 0.78 MAOB (0.77) GPR35USP2POLBHPGDALOX15
SCHEMBL22041606 0.78 GPR35 (0.71) GPR35USP2POLBHPGDALOX15
SCHEMBL2896018 0.77 GPR35 (0.63) GPR35USP2POLBHPGDALOX15
Hydrochloric Acid SCHEMBL11746382 0.76 GPR35 (0.61) GPR35USP2POLBHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2902388-B1 CONDENSATION PRODUCT OF THEANINE DERIVATIVE AND CARBOXYLIC ACID COUMARIN DERIVATIVE, INTERMEDIATE OF THE CONDENSATION PRODUCT, METHOD FOR PREPARING SAME, AND USE THEREOF SHANDONG YINGDONG YINGHAO BIOTECHNOLOGY INC (CN) 2019-03-13 EP disclosed
EP-2902388-B1 CONDENSATION PRODUCT OF THEANINE DERIVATIVE AND CARBOXYLIC ACID COUMARIN DERIVATIVE, INTERMEDIATE OF THE CONDENSATION PRODUCT, METHOD FOR PREPARING SAME, AND USE THEREOF SHANDONG YINGDONG YINGHAO BIOTECHNOLOGY INC (CN) 2019-03-13 EP disclosed
US-9518038-B2 Condensation product of theanine derivative and carboxylic acid coumarin derivative, its intermediate, preparation method and use thereof SHANDONG YINGDONG YINGHAO BIOTECHNOLOGY, INC. (CN) 2016-12-13 US disclosed
US-9518038-B2 Condensation product of theanine derivative and carboxylic acid coumarin derivative, its intermediate, preparation method and use thereof SHANDONG YINGDONG YINGHAO BIOTECHNOLOGY, INC. (CN) 2016-12-13 US disclosed
US-20150239861-A1 CONDENSATION PRODUCT OF THEANINE DERIVATIVE AND CARBOXYLIC ACID COUMARIN DERIVATIVE, ITS INTERMEDIATE, PREPARATION METHOD AND USE THEREOF ZHANG, GUOYING (CN) 2015-08-27 US disclosed
US-20150239861-A1 CONDENSATION PRODUCT OF THEANINE DERIVATIVE AND CARBOXYLIC ACID COUMARIN DERIVATIVE, ITS INTERMEDIATE, PREPARATION METHOD AND USE THEREOF ZHANG, GUOYING (CN) 2015-08-27 US disclosed
EP-2902388-A1 CONDENSATION PRODUCT OF THEANINE DERIVATIVE AND CARBOXYLIC ACID COUMARIN DERIVATIVE, INTERMEDIATE OF THE CONDENSATION PRODUCT, METHOD FOR PREPARING SAME, AND USE THEREOF Yantai University (CN) 2015-08-05 EP disclosed
CN-104144919-A CONDENSATION PRODUCT OF THEANINE DERIVATIVE AND CARBOXYLIC ACID COUMARIN DERIVATIVE, INTERMEDIATE OF THE CONDENSATION PRODUCT, METHOD FOR PREPARING SAME, AND USE THEREOF WUWEI COUNTY MARINE BIOTECHNOLOGY CO LTD 2014-11-12 CN disclosed
US-5482986-A ULTRAVIOLET RADIATION ABSORBER FOR THERMOPLASTIC RESINS; COLORLESS, HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-09 US disclosed
EP-0635504-A1 Benzopyran compound and use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-01-25 EP disclosed
US-4343938-A 7-[Dα-(Coumarin-3-carboxamido)arylacetamido]-cephalosporanic acids or salts AMERICAN CYANAMID COMPANY (US) 1982-08-10 US disclosed
US-4320133-A Penicillins and their antibacterial use SANDOZ LTD. (CH) 1982-03-16 US disclosed
US-4317774-A 6-[D-α-(Coumarin-3-carboxamido)arylacetamido]-penicillanic acids or salts AMERICAN CYANAMID COMPANY (US) 1982-03-02 US disclosed
EP-0003115-A1 Penicillins, per se and for use as antibacterially active antibiotics and their production SANDOZ AG (CH) 1979-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150239861-A1 CONDENSATION PRODUCT OF THEANINE DERIVATIVE AND CARBOXYLIC ACID COUMARIN DERIVATIVE, ITS INTERMEDIATE, PREPARATION METHOD AND USE THEREOF OGDH, C9, IRAK3 GPR35 3949/4885USP2 1903/4885POLB 1599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.