Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 9/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203829 | 0.82 | BCHE (0.38) | RORCSMN1; SMN2BCHEACHE | |
| SCHEMBL2203823 | 0.82 | BCHE (0.38) | RORCSMN1; SMN2BCHEACHE | |
| SCHEMBL12426460 | 0.78 | BCHE (0.37) | SLC6A9RORCTSHRMEN1KMT2A | |
| SCHEMBL2201883 | 0.77 | RORC (0.32) | RORCMEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL2201941 | 0.77 | RORC (0.37) | RORCMEN1KMT2ABCHEACHE | |
| SCHEMBL2200323 | 0.76 | MAOA (0.36) | BCHEACHE | |
| SCHEMBL2200327 | 0.76 | MAOA (0.36) | BCHEACHE | |
| SCHEMBL2204341 | 0.76 | RORC (0.47) | RORCMEN1KMT2ATMEM97SIGMAR1 | |
| SCHEMBL12509871 | 0.75 | RORC (0.37) | RORCPPARGBCHEACHE | |
| SCHEMBL4954388 | 0.73 | CA2 (0.38) | RORCSMN1; SMN2KMT2AGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |