Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 3/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.37 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199799 | 1.00 | FADS1 (0.40) | FADS1TRPM5TRPM4DRD3SLC6A4 | |
| SCHEMBL1686 | 1.00 | FADS1 (0.40) | FADS1TRPM5TRPM4DRD3SLC6A4 | |
| Oxalic Acid SCHEMBL15154934 | 0.92 | LMNA (0.42) | FADS1TRPM5TRPM4SLC6A4HTR7 | |
| SCHEMBL16312591 | 0.86 | FADS1 (0.39) | FADS1TRPM5TRPM4DRD3SLC6A4 | |
| SCHEMBL2812487 | 0.82 | KMT2A (0.45) | SLC6A4ALDH1A1BLMLMNA | |
| SCHEMBL6096441 | 0.78 | SLC6A2 (0.49) | SLC6A4SLC6A2NPC1ACHESLC6A3 | |
| SCHEMBL1777 | 0.78 | KDM1A (0.35) | SLC6A4HTR7 | |
| SCHEMBL4622856 | 0.74 | SLC5A2 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5936386 | 0.74 | MEN1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6655779 | 0.74 | NR3C1 (0.33) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659672-A1 | COMBINED USE OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS AND HEMATOPOIETIC GROWTH FACTORS FOR TREATING HEMATOPOIETIC DISEASES | Institut Gustave Roussy (FR) | 2020-06-03 | — | — | EP | disclosed |