Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 3/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.37 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199799 | 1.00 | FADS1 (0.40) | FADS1TRPM5TRPM4DRD3SLC6A4 | |
| SCHEMBL22043585 | 1.00 | FADS1 (0.40) | FADS1TRPM5TRPM4DRD3SLC6A4 | |
| Oxalic Acid SCHEMBL15154934 | 0.92 | LMNA (0.42) | FADS1TRPM5TRPM4SLC6A4HTR7 | |
| SCHEMBL16312591 | 0.86 | FADS1 (0.39) | FADS1TRPM5TRPM4DRD3SLC6A4 | |
| SCHEMBL2812487 | 0.82 | KMT2A (0.45) | SLC6A4ALDH1A1BLMLMNA | |
| SCHEMBL6096441 | 0.78 | SLC6A2 (0.49) | SLC6A4SLC6A2NPC1ACHESLC6A3 | |
| SCHEMBL1777 | 0.78 | KDM1A (0.35) | SLC6A4HTR7 | |
| SCHEMBL4622856 | 0.74 | SLC5A2 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5936386 | 0.74 | MEN1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6655779 | 0.74 | NR3C1 (0.33) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018351-A1 | PREPARATION OF ESCITALOPRAM | DR. REDDY'S LABORATORIES, INC. (US) | 2009-01-15 | — | — | US | claimed |
| EP-1706394-A4 | PREPARATION OF ESCITALOPRAM | REDDYS LAB INC DR (US) | 2008-10-22 | — | — | EP | claimed |
| US-7411077-B2 | Process for the preparation of a cyano-isobenzofuran | ADORKEN TECHNOLOGY SPA (IT) | 2008-08-12 | — | — | US | claimed |
| US-7255741-B2 | Process for the isolation of high purity crystalline citalopram base | JUBILANT ORGANOSYS LIMITED (IN) | 2007-08-14 | — | — | US | claimed |
| EP-1706394-A1 | PREPARATION OF ESCITALOPRAM | Dr. Reddy's Laboratories, Inc. (US) | 2006-10-04 | — | — | EP | claimed |
| US-20060183925-A1 | Process for the preparation of a cyano-isobenzofuran | ADORKEM TECHNOLOGY SPA | 2006-08-17 | — | — | US | claimed |
| US-20060167285-A1 | Production methods of citalopram and intermediates therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-07-27 | — | — | US | claimed |
| CN-1761658-A | Process for the preparation of a cyano-isobenzofuran | ADORKEM TECHNOLOGY SPA (IT) | 2006-04-19 | — | — | CN | claimed |
| EP-1601662-A1 | PROCESS FOR THE PREPARATION OF A CYANO-ISOBENZOFURAN | Adorkem Technology SpA (IT) | 2005-12-07 | — | — | EP | claimed |
| US-20050217562-A1 | Process for the isolation of high purity crystalline citalopram base | JUBILANT ORGANOSYS LIMITED (IN) | 2005-10-06 | — | — | US | claimed |
| WO-2005047274-A1 | PREPARATION OF ESCITALOPRAM | DR. REDDY'S LABORATORIES, INC. (US) | 2005-05-26 | — | — | WO | claimed |
| US-20050080278-A1 | Production methods of citalopram and intermediates therefor | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2005-04-14 | — | — | US | claimed |
| WO-2004080988-A1 | PROCESS FOR THE PREPARATION OF A CYANO-ISOBENZOFURAN | ADORKEM TECHNOLOGY SPA (IT) | 2004-09-23 | — | — | WO | claimed |
| WO-2003080590-A1 | PROCESS FOR THE ISOLATION OF HIGH PURITY CRYSTALLINE CITALOPRAM BASE | JUBILANT ORGANOSYS LTD. (GB) | 2003-10-02 | — | — | WO | claimed |
| EP-1346989-A1 | Improved process for the preparation of citalopram and its hydrobromide | Jubilant Organosys Limited (IN) | 2003-09-24 | — | — | EP | claimed |
| US-20030060640-A1 | Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans | H. LUNDBECK A/S (DK) | 2003-03-27 | — | — | US | claimed |
| EP-1274699-A1 | METHOD FOR THE PREPARATION OF 5-CYANO-1-(4-FLUOROPHENYL)-1,3-DIHYDROISOBENZOFURANS | H. Lundbeck A/S (DK) | 2003-01-15 | — | — | EP | claimed |
| WO-2001068632-A1 | METHOD FOR THE PREPARATION OF 5-CYANO-1-(4-FLUOROPHENYL)-1,3-DIHYDROISOBENZOFURANS | H. LUNDBECK A/S (DK) | 2001-09-20 | — | — | WO | claimed |
| EP-4347008-A1 | MAJOR DEPRESSIVE DISORDER OR PERSISTENT DEPRESSIVE DISORDER PREVENTION OR TREATMENT WITH LOW INTENSITY AND HIGH FREQUENCY MAGNETIC STIMULATION | Actipulse Neuroscience Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| US-4136193-A | ANTI-DEPRESSIVE SUBSTITUTED 1-DIMETHYLAMINOPROPYL-1-PHENYL PHTHALANS | KEFALAS A/S (DK) | 1979-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080278-A1 | Production methods of citalopram and intermediates therefor | TPH1, SLC6A4, CYP4F11 | FADS1 85/4885TRPM5 2105/4885TRPM4 2243/4885 |
| US-20060183925-A1 | Process for the preparation of a cyano-isobenzofuran | HTR1F, CYP4F12, CYP4F3 | FADS1 1665/4885TRPM5 1361/4885TRPM4 690/4885 |
| US-20030060640-A1 | Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans | DPYD, CYP2F1, CYP4F2 | FADS1 984/4885TRPM5 4314/4885TRPM4 4693/4885 |
| US-20060167285-A1 | Production methods of citalopram and intermediates therefor | TPH1, SLC6A4, CYP4F11 | FADS1 85/4885TRPM5 2105/4885TRPM4 2243/4885 |
| US-20090018351-A1 | PREPARATION OF ESCITALOPRAM | HTR4, SLC6A4, HTR5A | FADS1 1671/4885TRPM5 1038/4885TRPM4 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.