Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 19/20 | 0.48 |
| ▸ | KIT | P10721 | 9/20 | 0.44 |
| ▸ | ABL1 | P00519 | 8/20 | 0.44 |
| ▸ | BCR | P11274 | 8/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 12/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044102 | 0.85 | DDR1 (0.48) | DDR1KITABL1BCRDDR2 | |
| SCHEMBL22044874 | 0.83 | ABL1 (0.43) | ABL1BCRRIPK1 | |
| SCHEMBL22044907 | 0.79 | ROCK2 (0.45) | DDR1KITABL1BCRDDR2 | |
| SCHEMBL22044482 | 0.75 | HPGD (0.38) | DDR1RIPK1 | |
| SCHEMBL22043989 | 0.73 | HPGD (0.40) | DDR1 | |
| SCHEMBL27931784 | 0.73 | L3MBTL1 (0.52) | DDR1 | |
| SCHEMBL22044455 | 0.70 | HPGD (0.43) | — | |
| SCHEMBL27913563 | 0.69 | DDR1 (0.47) | DDR1RIPK1 | |
| SCHEMBL22044497 | 0.69 | MLYCD (0.48) | ABL1BCR | |
| SCHEMBL22044156 | 0.68 | DDR1 (0.41) | DDR1KITABL1BCRDDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | Amcure Biosciences Pte. Ltd. (SG) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | KRAS, NRAS, RASSF5 | DDR1 3947/4885KIT 287/4885ABL1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.