Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27887488 | 0.75 | NAPRT (0.43) | MAPTGAAALDH1A1MTNR1AMTNR1B | |
| SCHEMBL22044821 | 0.73 | PCSK9 (0.33) | GAAPCSK9ALDH1A1 | |
| SCHEMBL9253909 | 0.64 | MAPT (0.61) | MAPTKDM4EGAAHPGDALDH1A1 | |
| SCHEMBL12113186 | 0.64 | MAPT (0.61) | MAPTKDM4EGAAHPGDALDH1A1 | |
| SCHEMBL12440049 | 0.64 | MAPT (0.61) | MAPTKDM4EGAAHPGDALDH1A1 | |
| Phenyl Methyl Borinic Acid SCHEMBL120622 | 0.61 | — | — | |
| Phenylboronic Acid SCHEMBL3955122 | 0.61 | ENPP2 (0.88) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1265111 | 0.60 | TRPV6 (0.47) | KDM4EHPGDPCSK9ORAI1ORAI2 | |
| SCHEMBL734255 | 0.60 | — | — | |
| SCHEMBL7007899 | 0.60 | KCNN4 (0.48) | MAPTKDM4EGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052506-B1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | FLEXENABLE LTD (GB) | 2020-06-03 | — | — | EP | disclosed |