Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25257540 | 0.86 | PTGDR (0.44) | PTGDRHCRTR2HCRTR1KCNH2CYP2C8 | |
| SCHEMBL25301308 | 0.86 | PTGDR (0.44) | PTGDRHCRTR2HCRTR1KCNH2CYP2C8 | |
| SCHEMBL30046481 | 0.83 | HCRTR2 (0.36) | HCRTR2HCRTR1DDB1CRBNGPR119 | |
| SCHEMBL22045492 | 0.83 | HCRTR2 (0.36) | HCRTR2HCRTR1DDB1CRBNGPR119 | |
| SCHEMBL22044800 | 0.79 | PSEN1 (0.39) | PTGDRDDB1CRBNKCNH2CYP2C8 | |
| SCHEMBL30046221 | 0.79 | PSEN1 (0.39) | PTGDRDDB1CRBNKCNH2CYP2C8 | |
| SCHEMBL22045244 | 0.79 | HCRTR2 (0.33) | PTGDRHCRTR2HCRTR1KCNH2CYP2C8 | |
| SCHEMBL21988981 | 0.77 | HCRTR2 (0.40) | HCRTR2HCRTR1KCNH2CYP2C8CYP2C9 | |
| SCHEMBL21988980 | 0.77 | HCRTR2 (0.40) | HCRTR2HCRTR1KCNH2CYP2C8CYP2C9 | |
| SCHEMBL30047086 | 0.75 | KCNH2 (0.46) | HCRTR1KCNH2CYP2C8CYP2C9SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172512-A1 | Chemical Compounds | HBZ, HBB, HBS1L | PTGDR 623/4885HCRTR2 3239/4885HCRTR1 3191/4885 |
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | PTGDR 623/4885HCRTR2 3239/4885HCRTR1 3191/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | PTGDR 623/4885HCRTR2 3239/4885HCRTR1 3191/4885 |
| US-11014908-B2 | Chemical compounds | HBZ, HBB, HBS1L | PTGDR 623/4885HCRTR2 3239/4885HCRTR1 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.