SCHEMBL22044800

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30046221	1.00	PSEN1 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL21989074	0.86	PTGDR (0.48)	PTGDRPTGER2KCNH2CYP2C9CYP2C8
	SCHEMBL22044792	0.84	PSEN1 (0.41)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL22044799	0.84	ALDH1A1 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL22045988	0.81	KCNH2 (0.34)	KCNH2CYP2C9CYP2C8ALDH1A1KDM4E
	SCHEMBL22045494	0.79	PTGDR (0.34)	PTGDRFPR2PTPN1KCNH2CYP2C9
	SCHEMBL22044797	0.77	NR1I3 (0.43)	ALDH1A1MAPTMEN1KMT2ALMNA
	SCHEMBL30046219	0.75	KCNH2 (0.53)	PTGDRFPR2KCNH2CYP2C9CYP2C8
	SCHEMBL22044826	0.75	KCNH2 (0.42)	FPR2KCNH2CYP2C9CYP2C8ALDH1A1
	SCHEMBL22045492	0.74	HCRTR2 (0.36)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.