Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301308 | 1.00 | PTGDR (0.44) | PTGDRHTTHCRTR2HCRTR1MEN1 | |
| SCHEMBL22045494 | 0.86 | PTGDR (0.34) | PTGDRHCRTR2HCRTR1KCNH2CYP2C8 | |
| SCHEMBL22045244 | 0.83 | HCRTR2 (0.33) | PTGDRHTTHCRTR2HCRTR1MEN1 | |
| SCHEMBL21988981 | 0.81 | HCRTR2 (0.40) | HCRTR2HCRTR1MEN1KMT2AKCNH2 | |
| SCHEMBL21988980 | 0.81 | HCRTR2 (0.40) | HCRTR2HCRTR1MEN1KMT2AKCNH2 | |
| SCHEMBL21989007 | 0.81 | PTGDR (0.41) | PTGDRHTTHCRTR2HCRTR1MEN1 | |
| SCHEMBL21989074 | 0.77 | PTGDR (0.48) | PTGDRMEN1KMT2AKCNH2CYP2C8 | |
| SCHEMBL21988906 | 0.75 | MAPT (0.38) | HCRTR2HCRTR1MEN1KMT2AKCNH2 | |
| SCHEMBL21988907 | 0.75 | MAPT (0.38) | HCRTR2HCRTR1MEN1KMT2AKCNH2 | |
| SCHEMBL22046330 | 0.74 | ALDH1A1 (0.41) | HCRTR2HCRTR1MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | PTGDR 623/4885HTT 96/4885HCRTR2 3239/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | PTGDR 623/4885HTT 96/4885HCRTR2 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.