Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21988698 | 0.98 | MAPT (0.45) | MAPTKDM4EALDH1A1NPC1POLB | |
| SCHEMBL17627488 | 0.85 | CTSV (0.42) | MAPTKDM4EALDH1A1NPC1POLB | |
| SCHEMBL16004173 | 0.79 | KCNK2 (0.49) | MAPTKDM4EALDH1A1NPC1POLB | |
| SCHEMBL16364772 | 0.79 | MAPT (0.46) | MAPTKDM4EALDH1A1NPC1POLB | |
| SCHEMBL31586627 | 0.78 | KEAP1 (0.55) | MAPTKDM4EALDH1A1POLBKEAP1 | |
| SCHEMBL29133155 | 0.78 | MAPT (0.45) | MAPTKDM4EALDH1A1NPC1POLB | |
| Hydrochloric Acid SCHEMBL15994581 | 0.77 | KCNK2 (0.48) | MAPTKDM4EALDH1A1NPC1POLB | |
| Hydrochloric Acid SCHEMBL21988903 | 0.77 | KCNK2 (0.48) | MAPTKDM4EALDH1A1NPC1POLB | |
| Hydrochloric Acid SCHEMBL1786242 | 0.77 | MAPT (0.49) | MAPTKDM4EALDH1A1NPC1POLB | |
| Hydrochloric Acid SCHEMBL16320209 | 0.77 | MAPT (0.45) | MAPTKDM4EALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
| WO-2020109994-A1 | PYRAZOLES AS MODULATORS OF HEMOGLOBIN | PFIZER INC. (US) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172512-A1 | Chemical Compounds | HBZ, HBB, HBS1L | MAPT 305/4885KDM4E 2745/4885ALDH1A1 1737/4885 |
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | MAPT 305/4885KDM4E 2745/4885ALDH1A1 1737/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | MAPT 305/4885KDM4E 2745/4885ALDH1A1 1737/4885 |
| US-11014908-B2 | Chemical compounds | HBZ, HBB, HBS1L | MAPT 305/4885KDM4E 2745/4885ALDH1A1 1737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.