Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KLRK1 | P26718 | 9/20 | 0.38 |
| ▸ | MICA | Q29983 | 9/20 | 0.38 |
| ▸ | RAET1L | Q5VY80 | 9/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394775 | 0.85 | NPC1 (0.56) | NPC1POLBCTSSALDH1A1NTRK1 | |
| SCHEMBL18705566 | 0.81 | NPC1 (0.49) | NPC1POLBCTSSALDH1A1NTRK1 | |
| SCHEMBL18705673 | 0.79 | NPC1 (0.50) | NPC1POLBCTSSALDH1A1NTRK1 | |
| SCHEMBL3759581 | 0.77 | POLB (0.59) | NPC1POLBALDH1A1NTRK1MAPT | |
| SCHEMBL30620180 | 0.77 | NPC1 (0.53) | NPC1POLBALDH1A1NTRK1MAPT | |
| SCHEMBL21571478 | 0.77 | NPC1 (0.60) | NPC1POLBALDH1A1NTRK1MAPT | |
| SCHEMBL5106559 | 0.77 | NPC1 (0.53) | NPC1POLBALDH1A1NTRK1MAPT | |
| SCHEMBL29100737 | 0.77 | NPC1 (0.53) | NPC1POLBALDH1A1NTRK1MAPT | |
| SCHEMBL15244373 | 0.77 | NPC1 (0.62) | NPC1POLBALDH1A1NTRK1MAPT | |
| SCHEMBL3692138 | 0.76 | NPC1 (0.56) | NPC1POLBALDH1A1NTRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659438-A1 | COMPOUNDS AND COMPOSITIONS HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST INSECT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-03 | — | — | EP | disclosed |