SCHEMBL22048781

SCHEMBL22048781

Clc1nc2ccccc2c2c3ccccc3c3c4ccccc4c4ccccc4c3c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
MAOA P21397 2/20 0.50
MAOB P27338 1/20 0.50
KDM4E B2RXH2 5/20 0.44
PKM P14618 1/20 0.44
KMT2A Q03164 4/20 0.42
GPR3 P46089 1/20 0.42
ALDH1A1 P00352 5/20 0.41
PDE4A P27815 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41
HPGD P15428 3/20 0.40
HSD17B10 Q99714 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
GLA P06280 3/20 0.40
CASP1 P29466 2/20 0.40
CASP7 P55210 2/20 0.40
CHRM2 P08172 1/20 0.40
ADRA2A P08913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL516091 0.78 TDP1 (0.59) TDP1MAOAMAOBKDM4EPKM
SCHEMBL22048782 0.73 NUDT1 (0.48) TDP1KDM4EPKMKMT2AALDH1A1
SCHEMBL22049785 0.73 ENPP1 (0.47) TDP1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL21537700 0.72 GPR3 (0.65) TDP1MAOAMAOBKDM4EGPR3
SCHEMBL6679033 0.71 MAOA (0.70) TDP1MAOAMAOBKDM4EPKM
SCHEMBL18456032 0.71 KDM4E (0.53) TDP1MAOAMAOBKDM4EPKM
SCHEMBL841604 0.71 POLB (0.46) TDP1MAOAMAOBKDM4EPKM
SCHEMBL14990360 0.70 GUSB (0.48) MAOBKDM4EPKMKMT2AALDH1A1
SCHEMBL29175203 0.70 MAOA (0.67) TDP1MAOAMAOBKDM4EPKM
Water SCHEMBL27739698 0.70 MAOA (0.67) TDP1MAOAMAOBKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020111140-A1 FUSED RING COMPOUND, PRODUCTION METHOD THEREFOR, AND ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL 東ソー株式会社 2020-06-04 WO disclosed