Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19069989 | 0.85 | TDP1 (0.37) | HTTSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL21160747 | 0.73 | TSHR (0.40) | HTTSMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL20999268 | 0.69 | — | — | |
| SCHEMBL11547843 | 0.69 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL16683037 | 0.66 | TDP1 (0.78) | HTTSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL16590863 | 0.66 | TDP1 (0.78) | HTTSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL21795331 | 0.65 | HTT (0.57) | HTTSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL8941654 | 0.64 | PTGS2 (0.56) | HTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL21653914 | 0.64 | SOS1 (0.55) | HTTSMN1; SMN2LMNATSHRSOS1 | |
| SCHEMBL6090901 | 0.64 | ALDH1A1 (0.58) | HTTSMN1; SMN2LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793680-B2 | Bridged silicone resin, film, electronic device and related methods | DOW SILICONES CORPORATION (US) | 2020-10-06 | — | — | US | disclosed |
| US-20200172679-A1 | BRIDGED SILICONE RESIN, FILM, ELECTRONIC DEVICE AND RELATED METHODS | DOW SILICONES CORPORATION | 2020-06-04 | — | — | US | disclosed |