Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051882 | 0.91 | HDAC2 (0.44) | KIF11ALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL22050421 | 0.85 | KIF11 (0.46) | KIF11ALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL22051845 | 0.78 | HDAC2 (0.44) | KIF11ALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL16372579 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL22044362 | 0.77 | SMN1; SMN2 (0.51) | KIF11ALDH1A1CYP3A4THRBSMN1; SMN2 | |
| SCHEMBL3378902 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL22050632 | 0.75 | ALDH1A1 (0.45) | KIF11ALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL25048 | 0.74 | CA4 (0.56) | KIF11KMT2AKCNH2CA4LTA4H | |
| SCHEMBL4570566 | 0.74 | CA4 (0.56) | KIF11KMT2AKCNH2CA4LTA4H | |
| SCHEMBL10686605 | 0.74 | ESR1 (0.45) | ALDH1A1CYP3A4MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172470-A1 | NOVEL (POLY)AMINE COMPOUND, RESIN AND CURED PRODUCT | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172470-A1 | NOVEL (POLY)AMINE COMPOUND, RESIN AND CURED PRODUCT | PAM, CBR1, KDM1A | KIF11 3949/4885ALDH1A1 276/4885CYP3A4 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.