Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 8/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23888878 | 1.00 | S1PR5 (0.40) | S1PR5KMT2AP2RY14DRD1DRD5 | |
| SCHEMBL22051935 | 0.84 | USP5 (0.51) | S1PR5KMT2AMAPTUSP5 | |
| SCHEMBL22050486 | 0.84 | USP5 (0.51) | S1PR5KMT2AMAPTUSP5 | |
| SCHEMBL22051934 | 0.83 | S1PR5 (0.39) | S1PR5KMT2AP2RY14DRD1DRD5 | |
| SCHEMBL22051258 | 0.77 | USP5 (0.46) | KMT2AMAPTUSP5 | |
| SCHEMBL22051259 | 0.77 | KMT2A (0.36) | S1PR5KMT2AP2RY14DRD1DRD5 | |
| SCHEMBL22050821 | 0.77 | MGLL (0.35) | S1PR5KMT2AP2RY14DRD1DRD5 | |
| SCHEMBL22050820 | 0.77 | USP5 (0.44) | P2RY14MGLLMAPTUSP5 | |
| SCHEMBL22051926 | 0.76 | USP5 (0.45) | P2RY14MAPTUSP5 | |
| SCHEMBL18054903 | 0.75 | ALDH1A1 (0.45) | S1PR5SLC6A7S1PR2MAOBSLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |