Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18039013 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1MAPTKDM4ECYP3A4CYP2D6 | |
| SCHEMBL18038967 | 0.79 | GAA (0.47) | ALDH1A1MAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL30207105 | 0.79 | GAA (0.47) | ALDH1A1MAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL18038998 | 0.78 | GAA (0.46) | ALDH1A1MAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL22051931 | 0.76 | GAA (0.42) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL22051970 | 0.75 | KIF11 (0.40) | MAPTS1PR5KIF11SMN1; SMN2GRIN2B | |
| SCHEMBL23888878 | 0.75 | S1PR5 (0.40) | MAPTS1PR5S1PR2SLC6A7SLC13A5 | |
| SCHEMBL22050485 | 0.75 | S1PR5 (0.40) | MAPTS1PR5S1PR2SLC6A7SLC13A5 | |
| SCHEMBL22051935 | 0.74 | USP5 (0.51) | ALDH1A1MAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL22050486 | 0.74 | USP5 (0.51) | ALDH1A1MAPTPOLBCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016136985-A1 | PYRIDINONE COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2016-09-01 | — | — | WO | disclosed |