Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050452 | 0.80 | L3MBTL1 (0.44) | TRIM24TRIM33RAB9ASMN1; SMN2CA12 | |
| SCHEMBL22050500 | 0.79 | HPGD (0.41) | MKNK1MKNK2RAB9ASMN1; SMN2 | |
| SCHEMBL22051941 | 0.79 | LMNA (0.34) | MKNK1MKNK2RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22051928 | 0.76 | GRIN2B (0.38) | MKNK1MKNK2GRIN2B | |
| SCHEMBL22051934 | 0.74 | S1PR5 (0.39) | MKNK1MKNK2 | |
| SCHEMBL22050454 | 0.72 | L3MBTL1 (0.44) | RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22050824 | 0.72 | LMNA (0.35) | CA1CA2CA9LMNA | |
| SCHEMBL22051332 | 0.71 | DRD2 (0.34) | MKNK1MKNK2RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18038965 | 0.69 | L3MBTL1 (0.52) | MKNK1MKNK2SMN1; SMN2LMNA | |
| SCHEMBL23888898 | 0.68 | DRD2 (0.32) | MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888651-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | Kyushu University, National University Corporation (JP) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |