Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050499 | 0.82 | L3MBTL1 (0.45) | GRIN2BCYP1A2SCN9AMAPTGAA | |
| SCHEMBL22050494 | 0.76 | TRIM24 (0.41) | GRIN2BMKNK1MKNK2 | |
| SCHEMBL22050500 | 0.75 | HPGD (0.41) | MKNK1MKNK2 | |
| SCHEMBL22051934 | 0.72 | S1PR5 (0.39) | MKNK1MKNK2 | |
| SCHEMBL22051941 | 0.71 | LMNA (0.34) | MKNK1MKNK2HTR1A | |
| SCHEMBL22050824 | 0.70 | LMNA (0.35) | — | |
| SCHEMBL22051360 | 0.69 | GRIN2B (0.36) | GRIN2BGRIN1MAPTCYP2C19 | |
| SCHEMBL23888887 | 0.67 | P2RY14 (0.38) | CHRM2HTR1ADRD2 | |
| SCHEMBL22051332 | 0.67 | DRD2 (0.34) | GRIN2BMKNK1MKNK2DRD2 | |
| SCHEMBL22051948 | 0.67 | GRIN2B (0.38) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |