Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283086 | 0.94 | MAPT (0.58) | MAPTS1PR4TDP1HPGDTSHR | |
| SCHEMBL895104 | 0.90 | S1PR4 (0.58) | MAPTS1PR4TDP1HPGDTSHR | |
| SCHEMBL11413525 | 0.86 | S1PR4 (0.66) | MAPTS1PR4TDP1 | |
| SCHEMBL7237501 | 0.84 | MAPT (0.58) | MAPTS1PR4TDP1HPGDTSHR | |
| SCHEMBL31343622 | 0.83 | MAPT (0.48) | MAPTS1PR4HPGDTSHRRAB9A | |
| SCHEMBL9214093 | 0.82 | MAPT (0.57) | MAPTS1PR4TDP1HPGDTSHR | |
| SCHEMBL11840387 | 0.82 | TDP1 (0.56) | MAPTS1PR4TDP1HPGDTSHR | |
| SCHEMBL5318910 | 0.81 | S1PR4 (0.47) | MAPTS1PR4SMN1; SMN2 | |
| SCHEMBL8794130 | 0.81 | TP53 (0.64) | MAPTS1PR4TDP1HPGDTSHR | |
| SCHEMBL5477791 | 0.81 | ALDH1A1 (0.68) | MAPTS1PR4TDP1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024229078-A1 | MONOAMINE OXIDASE INHIBITORS | ELLISON INSTITUTE, LLC (US) | 2024-11-07 | — | — | WO | disclosed |
| EP-2736506-B1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIV SOUTHERN CALIFORNIA (US) | 2018-09-05 | — | — | EP | disclosed |
| US-20180185303-A1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180185303-A1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180185303-A1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-07-05 | — | — | US | disclosed |
| US-9771625-B2 | Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771625-B2 | Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771625-B2 | Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-09-26 | — | — | US | disclosed |
| WO-2016077541-A1 | NOVEL ANTI-INFECTIVE COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-05-19 | — | — | WO | disclosed |
| EP-2134685-B1 | 7-NONSUBSTITUTED INDOLE DERIVATIVES AS MCL-1 INHIBITORS | ABBVIE INC (US) | 2015-09-02 | — | — | EP | disclosed |
| WO-2008130970-A1 | 7-NONSUBSTITUTED INDOLE MCL-1 INHIBITORS | ABBOTT LABORATORIES (US) | 2008-10-30 | — | — | WO | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253178-B2 | Carboxylic acids | EISAI CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20040116708-A1 | Insulin sensitizers; antidiabetic agents, antiinflammatory agents; inflammatory bowel disorders | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| CN-1503774-A | Carboxylic acid derivatives and salts thereof | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
| EP-1375484-A1 | CARBOXYLIC ACIDS | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-4913891-A | CARBON-11 LABELED CLORGYLINE AND L-DEPRENYL BOUND TO MONO-OXIDASE; IRREVERSIBLE; MAPPING ENZYME ACITIVITY | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1990-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | MAPT 4654/4885S1PR4 1536/4885TDP1 4437/4885 |
| US-20180185303-A1 | MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER | MAOA, COMT, MAOB | MAPT 592/4885S1PR4 3400/4885TDP1 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.