Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051299 | 0.86 | TRPV6 (0.43) | TLR9TRPV6JAK2PTK2ENPP2 | |
| SCHEMBL22050487 | 0.86 | TRPV6 (0.43) | TLR9TRPV6JAK2PTK2ENPP2 | |
| SCHEMBL22050475 | 0.80 | TLR9 (0.39) | TLR9TRPV6JAK2TLR8TLR7 | |
| SCHEMBL22051257 | 0.78 | KCNH2 (0.46) | CCR2KCNH2 | |
| SCHEMBL23888886 | 0.77 | IL2 (0.32) | TLR9JAK2MAP4K1PTK2IL2 | |
| SCHEMBL22051958 | 0.76 | TLR9 (0.35) | TLR9TRPV6JAK2TLR8TLR7 | |
| SCHEMBL22051314 | 0.74 | TNKS (0.33) | TRPV6 | |
| SCHEMBL22051955 | 0.72 | CHRNB2 (0.40) | — | |
| SCHEMBL22051332 | 0.68 | DRD2 (0.34) | CCR2 | |
| SCHEMBL17210747 | 0.66 | NPC1 (0.42) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888651-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | Kyushu University, National University Corporation (JP) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |