Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050487 | 1.00 | TRPV6 (0.43) | TRPV6KDRTLR9OXTRSCD | |
| SCHEMBL22050475 | 0.87 | TLR9 (0.39) | TRPV6TLR9SCDSCD5KIT | |
| SCHEMBL22051254 | 0.86 | CCR2 (0.37) | TRPV6TLR9JAK2PTK2ENPP2 | |
| SCHEMBL22051958 | 0.82 | TLR9 (0.35) | TRPV6TLR9HSD17B1HSD17B2JAK2 | |
| SCHEMBL23888886 | 0.79 | IL2 (0.32) | TLR9JAK2PTK2 | |
| SCHEMBL22051955 | 0.76 | CHRNB2 (0.40) | NPC1 | |
| SCHEMBL22051298 | 0.76 | HTR2B (0.51) | MEN1KMT2ALMNA | |
| SCHEMBL22050484 | 0.76 | HTR2B (0.51) | MEN1KMT2ALMNA | |
| SCHEMBL22051331 | 0.71 | TRPV6 (0.40) | TRPV6SCDNPC1 | |
| SCHEMBL22050493 | 0.71 | TRPV6 (0.40) | TRPV6SCDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |