Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 4/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051956 | 0.71 | MAPT (0.45) | POLB | |
| SCHEMBL22051360 | 0.71 | GRIN2B (0.36) | GRIN2BPOLB | |
| SCHEMBL22050483 | 0.66 | MKNK1 (0.41) | — | |
| SCHEMBL21749674 | 0.64 | L3MBTL1 (0.46) | POLB | |
| SCHEMBL22050825 | 0.62 | MAPT (0.50) | POLB | |
| SCHEMBL23888878 | 0.61 | S1PR5 (0.40) | — | |
| SCHEMBL23888894 | 0.59 | POLB (0.37) | ICMTGRIN2BPOLB | |
| SCHEMBL20195342 | 0.59 | HRH3 (0.42) | POLB | |
| SCHEMBL13680438 | 0.58 | LMNA (0.67) | POLB | |
| SCHEMBL21749673 | 0.58 | ALDH1A1 (0.50) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888651-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | Kyushu University, National University Corporation (JP) | 2021-10-06 | — | — | EP | disclosed |