Sugi Predict

Sugi Predict / Compounds / SCHEMBL2205265

SCHEMBL2205265

SCHEMBL2205265

CC(C)(C)N([C@@H](CC(=O)O)C(=O)O)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ MAPT P10636 1/20 0.35
▸ SLC22A6 Q4U2R8 1/20 0.35
▸ PGD P52209 1/20 0.32
▸ FOLH1 Q04609 2/20 0.32
▸ HMGCR P04035 1/20 0.32
▸ CHRM1 P11229 1/20 0.32
▸ TBXA2R P21731 1/20 0.32
▸ ADRA1A P35348 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ CYP2D6 P10635 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ HIF1A Q16665 1/20 0.31
▸ GABRR1 P24046 2/20 0.30
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9080606 1.00 TDP1 (0.39) TDP1SMN1; SMN2MAPTSLC22A6PGD
Hydrochloric Acid SCHEMBL918666 0.98 TDP1 (0.37) TDP1SMN1; SMN2MAPTSLC22A6PGD
Hydrochloric Acid SCHEMBL19384699 0.98 TDP1 (0.37) TDP1SMN1; SMN2MAPTSLC22A6PGD
Hydrochloric Acid SCHEMBL27802580 0.98 TDP1 (0.37) TDP1SMN1; SMN2MAPTSLC22A6PGD
SCHEMBL30734437 0.80 TDP1 (0.37) TDP1SMN1; SMN2MAPTSLC22A6PGD
SCHEMBL9189097 0.79 TET2 (0.45) —
SCHEMBL5571470 0.78 CYP1A2 (0.45) FOLH1
SCHEMBL5571472 0.78 CYP1A2 (0.45) FOLH1
SCHEMBL9219251 0.78 CYP1A2 (0.45) FOLH1
Hydrochloric Acid SCHEMBL3471976 0.77 CYP1A2 (0.43) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719602-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-04-08 — — EP disclosed
US-12478081-B2 Application of aspartic acid derivative in preparing animal feed additive Anipha Technologies Pty Ltd (AU) 2025-11-25 — — US disclosed
EP-4626489-A1 PCTA DERIVATIVES, CONJUGATES THEREOF AND USES THEREOF Novartis AG (CH) 2025-10-08 — — EP disclosed
US-12302927-B2 Application of aspartic acid derivative in preparing animal feed additive Anipha Technologies Pty Ltd (AU) 2025-05-20 — — US disclosed
US-20250051375-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. 2025-02-13 — — US disclosed
WO-2024249517-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. (US) 2024-12-05 — — WO disclosed
US-20240284937-A1 APPLICATION OF ASPARTIC ACID DERIVATIVE IN PREPARING ANIMAL FEED ADDITIVE Anipha Technologies Pty Ltd (AU) 2024-08-29 — — US disclosed
CN-118369325-A Therapeutic compounds for HIV virus infection 吉利德科学公司 2024-07-19 — — CN disclosed
WO-2024116053-A1 PCTA DERIVATIVES, CONJUGATES THEREOF AND USES THEREOF NOVARTIS AG (CH) 2024-06-06 — — WO disclosed
CN-116789559-A Synthesis method of aspergillin A and analogues thereof 华南理工大学 2023-09-22 — — CN disclosed
US-20050009863-A1 Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-01-13 — — US disclosed
EP-1443964-A1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF HAIR LOSS QLT Inc. (CA) 2004-08-11 — — EP disclosed
WO-2003039596-A1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF HAIR LOSS QLT INC. (CA) 2003-05-15 — — WO disclosed
US-6506738-B1 Treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection. BRISTOL-MYERS SQUIBB COMPANY 2003-01-14 — — US disclosed
WO-2002026228-A1 BENZIMIDAZOLONE ANTIVIRAL AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-04-04 — — WO disclosed
US-5506255-A ORGANIC PIGMENTS, FLUORESCENT DYES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-04-09 — — US disclosed
EP-0632040-A1 Antibacterial imidazole derivatives Takeda Chemical Industries, Ltd. (JP) 1995-01-04 — — EP disclosed
US-5260277-A Cell receptor antagonists TANABE SEIYAKU CO., LTD. (JP) 1993-11-09 — — US disclosed
US-4892733-A DRUG DELIVERY, HOMO-AND CO-POLYMERS OF ASPARTIC AND GLUTAMIC ACID IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-01-09 — — US disclosed
US-4301065-A Novel polypeptides having thymic activity or an antagonistic activity and processes for their synthesis AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1981-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12478081-B2 Application of aspartic acid derivative in preparing animal feed additive AADAT, SLC1A5, SLC1A3 TDP1 4171/4885SMN1; SMN2 1393/4885MAPT 477/4885
US-12302927-B2 Application of aspartic acid derivative in preparing animal feed additive AADAT, SLC1A5, SLC1A3 TDP1 4181/4885SMN1; SMN2 1483/4885MAPT 342/4885
US-20240284937-A1 APPLICATION OF ASPARTIC ACID DERIVATIVE IN PREPARING ANIMAL FEED ADDITIVE AADAT, SLC1A5, SLC1A3 TDP1 4171/4885SMN1; SMN2 1393/4885MAPT 477/4885
US-20050009863-A1 Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines CYP27A1, CYP11B2, CYP7A1 TDP1 3331/4885SMN1; SMN2 433/4885MAPT 3039/4885
US-20250051375-A1 ANTI-HIV COMPOUNDS CCR5, CD4, NFATC1 TDP1 4034/4885SMN1; SMN2 2817/4885MAPT 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.