Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ILK | Q13418 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231307 | 0.86 | KDM4E (0.75) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12854008 | 0.84 | KDM4E (0.72) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL827403 | 0.80 | RAB9A (0.67) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2138149 | 0.79 | KDM4E (0.66) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8617042 | 0.78 | KDM4E (0.64) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2225061 | 0.78 | KDM4E (0.64) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL914476 | 0.78 | KDM4E (1.00) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5545830 | 0.78 | KDM4E (0.64) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4412613 | 0.78 | RAB9A (0.64) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL196475 | 0.78 | KDM4E (0.73) | KDM4ENPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127145-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |