SCHEMBL22054559

SCHEMBL22054559

CC(=O)CCSSC(C)(C)CC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
LMNA P02545 2/20 0.36
SLC15A2 Q16348 1/20 0.36
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24220964 0.83
SCHEMBL2128079 0.77 TSHR (0.50) LMNASLC15A2TSHR
SCHEMBL31462479 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL11529618 0.74 ALDH1A1 (0.56) ALDH1A1LMNASLC15A2TSHR
SCHEMBL7609868 0.73 TSHR (0.31) LMNATSHR
SCHEMBL16646712 0.72 ACHE (0.33) ALDH1A1
SCHEMBL24220981 0.71
SCHEMBL17660545 0.70 CTSD (0.37) LMNA
SCHEMBL19733543 0.69 ALDH1A1 (0.34) ALDH1A1
SCHEMBL19733437 0.68 ALDH1A1 (0.38) ALDH1A1LMNASLC15A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020107078-A1 DENDRIMER FOR THERAPY AND IMAGING STARPHARMA PTY LTD (AU) 2020-06-04 WO disclosed