Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 8/20 | 0.72 |
| ▸ | EP300 | Q09472 | 3/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.58 |
| ▸ | KAT2A | Q92830 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996046 | 0.90 | KAT2B (0.61) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL17502095 | 0.84 | KAT2B (1.00) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL22056075 | 0.84 | KAT2B (0.54) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL20022707 | 0.81 | CASP3 (0.68) | KAT2BKAT2AHDAC3HDAC1HDAC8 | |
| SCHEMBL22056077 | 0.80 | KAT2B (0.69) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL22056078 | 0.77 | KAT2B (0.50) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL20022697 | 0.77 | P4HB (0.69) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL18872059 | 0.74 | KAT2B (1.00) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL17515276 | 0.73 | KAT2B (1.00) | KAT2BEP300CREBBPKAT2AHDAC3 | |
| SCHEMBL17515280 | 0.72 | KAT2B (0.76) | KAT2BEP300CREBBPKAT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113222-A1 | NEUROPROTECTIVE PDI MODULATING SMALL MOLECULES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-06-04 | — | — | WO | disclosed |