SCHEMBL2206076

SCHEMBL2206076

Cc1cccc(N(S(=O)(=O)C(F)(F)F)S(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.46
LMNA P02545 2/20 0.40
POLB P06746 2/20 0.40
ACHE P22303 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PKM P14618 1/20 0.37
GLA P06280 1/20 0.37
RAB9A P51151 1/20 0.37
HTT P42858 1/20 0.37
HSD17B1 P14061 2/20 0.36
HSD17B2 P37059 2/20 0.36
SDHB P21912 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2998340 0.80 MEN1 (0.39) POLBACHEALDH1A1PTGS1PTGS2
SCHEMBL2202278 0.79 MAPT (0.44) LMNAALDH1A1RAB9AHTTPTGS1
SCHEMBL12228137 0.77 POLB (0.51) RECQLLMNAPOLBACHEALDH1A1
SCHEMBL2199940 0.77 CA9 (0.47) LMNAALDH1A1HPGDHTTPTGS2
SCHEMBL64494 0.77 CA2 (0.43) POLBALDH1A1PKMPTGS1PTGS2
SCHEMBL2202018 0.75 MEN1 (0.43) LMNAPOLBALDH1A1HPGDHSD17B10
SCHEMBL5537074 0.74 CA1 (0.30) ALDH1A1
SCHEMBL3529751 0.73 POLB (0.48) POLBALDH1A1RAB9ASDHB
SCHEMBL16984377 0.71 AR (0.38) ALDH1A1CYP3A4
SCHEMBL816352 0.71 ACHE (0.46) RECQLLMNAPOLBACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160102159-A1 Olefin Polymerization Catalyst and a Combined Catalyst Containing the Same PETROCHINA COMPANY LIMITED (CN) 2016-04-14 US claimed
US-8470941-B2 Catalyst for homopolymerizing and copolymerizing propylene and its preparation and use PETROCHINA COMPANY LIMITED (CN) 2013-06-25 US claimed
US-8404789-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2013-03-26 US claimed
EP-2159232-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2012-11-21 EP claimed
US-20110207900-A1 CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE PETROCHINA COMPANY LIMITED (CN) 2011-08-25 US claimed
EP-2345675-A1 A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE Petrochina Company Limited (CN) 2011-07-20 EP claimed
US-20100184930-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2010-07-22 US claimed
EP-2159232-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2010-03-03 EP claimed
US-20160102159-A1 Olefin Polymerization Catalyst and a Combined Catalyst Containing the Same PETROCHINA COMPANY LIMITED (CN) 2016-04-14 US disclosed
US-8470941-B2 Catalyst for homopolymerizing and copolymerizing propylene and its preparation and use PETROCHINA COMPANY LIMITED (CN) 2013-06-25 US disclosed
US-8404789-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2013-03-26 US disclosed
EP-2159232-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2012-11-21 EP disclosed
US-20110207900-A1 CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE PETROCHINA COMPANY LIMITED (CN) 2011-08-25 US disclosed
EP-2345675-A1 A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE Petrochina Company Limited (CN) 2011-07-20 EP disclosed
US-20100184930-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2010-07-22 US disclosed
EP-2159232-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2010-03-03 EP disclosed