SCHEMBL2199940

SCHEMBL2199940

Cc1ccc(N(S(=O)(=O)C(F)(F)F)S(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 4/20 0.47
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA5A P35218 2/20 0.47
MAPT P10636 2/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
GAA P10253 1/20 0.38
RORC P51449 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AGER Q15109 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
GFER P55789 1/20 0.36
MCL1 Q07820 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA12 O43570 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2295332 0.81 CA9 (0.42) CA9CA1CA2CA5AMAPT
SCHEMBL2206162 0.81 NR1I2 (0.36) CA9CA1CA2ALDH1A1TSHR
SCHEMBL2204636 0.80 PKM (0.45) CA9CA1CA2MAPTALDH1A1
SCHEMBL19376860 0.80 CA1 (0.43) CA9CA1CA2CA5AALDH1A1
SCHEMBL10141931 0.79 ALDH1A1 (0.41) CA9CA1CA2CA5AALDH1A1
SCHEMBL64494 0.78 CA2 (0.43) CA9CA1CA2CA5AALDH1A1
SCHEMBL2206076 0.77 RECQL (0.46) ALDH1A1HTTLMNAHPGDPTGS2
SCHEMBL26310493 0.76 MAPT (0.47) CA9CA1CA2CA5AMAPT
SCHEMBL5537074 0.75 CA1 (0.30) CA1CA2ALDH1A1CA7
SCHEMBL942014 0.75 TDP1 (0.41) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160102159-A1 Olefin Polymerization Catalyst and a Combined Catalyst Containing the Same PETROCHINA COMPANY LIMITED (CN) 2016-04-14 US claimed
US-8470941-B2 Catalyst for homopolymerizing and copolymerizing propylene and its preparation and use PETROCHINA COMPANY LIMITED (CN) 2013-06-25 US claimed
US-8404789-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2013-03-26 US claimed
EP-2159232-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2012-11-21 EP claimed
US-20110207900-A1 CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE PETROCHINA COMPANY LIMITED (CN) 2011-08-25 US claimed
US-20100184930-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2010-07-22 US claimed
EP-2159232-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2010-03-03 EP claimed
US-20160102159-A1 Olefin Polymerization Catalyst and a Combined Catalyst Containing the Same PETROCHINA COMPANY LIMITED (CN) 2016-04-14 US disclosed
US-8470941-B2 Catalyst for homopolymerizing and copolymerizing propylene and its preparation and use PETROCHINA COMPANY LIMITED (CN) 2013-06-25 US disclosed
US-8404789-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2013-03-26 US disclosed
EP-2159232-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2012-11-21 EP disclosed
US-20110207900-A1 CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE PETROCHINA COMPANY LIMITED (CN) 2011-08-25 US disclosed
EP-2345675-A1 A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE Petrochina Company Limited (CN) 2011-07-20 EP disclosed
US-20100184930-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2010-07-22 US disclosed
EP-2159232-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2010-03-03 EP disclosed