Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871378 | 0.84 | ALDH1A1 (0.32) | ALDH1A1MAPK1CYP3A4MAPT | |
| SCHEMBL2399625 | 0.77 | CYP3A4 (0.44) | ACHESIGMAR1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL28092078 | 0.75 | ACHE (0.52) | ACHESIGMAR1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL6745564 | 0.74 | TSHR (0.48) | SIGMAR1ALDH1A1MAPK1CYP3A4MAPT | |
| SCHEMBL27984773 | 0.74 | MAPT (0.52) | CETPALDH1A1CYP3A4CYP2C19HTT | |
| SCHEMBL977663 | 0.74 | ACHE (0.58) | ACHESIGMAR1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL23977864 | 0.72 | AR (0.41) | ACHECETPSIGMAR1ALDH1A1CYP3A4 | |
| SCHEMBL29692933 | 0.72 | ACHE (0.55) | ACHESIGMAR1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL12879 | 0.72 | ALDH1A1 (0.56) | ACHESIGMAR1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL29381010 | 0.72 | ALDH1A1 (0.56) | ACHESIGMAR1ALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067625-B2 | Fluorosurfactants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-8049022-B2 | Fluorosurfactants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20100152081-A1 | Fluorosurfactants | MERCK PATENT GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20090312432-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090264525-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| US-4731450-A | Process for perfluoroalkylation of aromatic derivatives | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312432-A1 | FLUOROSURFACTANTS | SGMS2, FASN, SGMS1 | ACHE 4091/4885CETP 132/4885SIGMAR1 512/4885 |
| US-20100152081-A1 | Fluorosurfactants | CBR3, FPR3, NOX3 | ACHE 3673/4885CETP 1859/4885SIGMAR1 347/4885 |
| US-20090264525-A1 | FLUOROSURFACTANTS | FASN, FFAR3, SGMS2 | ACHE 4537/4885CETP 83/4885SIGMAR1 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.