Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26026410 | 0.84 | MAP2K1 (0.40) | MAP2K1CSNK1DCSNK1G2GAAUSP30 | |
| SCHEMBL22060849 | 0.83 | ABCC9 (0.40) | MAP2K1TBXA2RCSNK1DCSNK1G2ABCC9 | |
| SCHEMBL19698925 | 0.80 | TBXA2R (0.40) | TBXA2RCSNK1DABCC9ABCC8KCNJ11 | |
| SCHEMBL9232027 | 0.79 | MAP2K1 (0.42) | MAP2K1CSNK1DCSNK1G2GAAUSP30 | |
| SCHEMBL11200089 | 0.79 | MMP13 (0.46) | MAP2K1TBXA2RABCB1GAAUSP30 | |
| SCHEMBL11200087 | 0.79 | MMP13 (0.46) | MAP2K1TBXA2RABCB1GAAUSP30 | |
| SCHEMBL2339309 | 0.79 | KDM4E (0.54) | TBXA2RABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL2814661 | 0.79 | PDK1 (0.47) | ABCC9ABCC8KCNJ11KCNJ8ABCB1 | |
| SCHEMBL5652691 | 0.77 | PKM (0.39) | MAP2K1CSNK1DCSNK1G2ABCC9ABCC8 | |
| SCHEMBL21184436 | 0.76 | TBXA2R (0.40) | TBXA2RABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108538-A1 | RORγ INHIBITOR HAVING SULFONYL STRUCTURE | 正大天晴药业集团股份有限公司 | 2020-06-04 | — | — | WO | disclosed |