SCHEMBL22062012

SCHEMBL22062012

c1ccc2c(/N=N/Nc3cccc4ccccc34)cccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GRIN1 Q05586 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2B Q13224 1/20 0.50
GRIN2C Q14957 1/20 0.50
GRIN3A Q8TCU5 1/20 0.50
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 4/20 0.44
CYP3A4 P08684 3/20 0.44
HPGD P15428 3/20 0.44
TSHR P16473 3/20 0.44
ALOX15 P16050 2/20 0.44
TP53 P04637 1/20 0.44
CDC25B P30305 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ABCB11 O95342 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4908899 1.00 SIGMAR1 (0.50) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1572609 0.81 TSHR (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8520862 0.81 TDP1 (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8520861 0.81 TDP1 (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1348095 0.81 TSHR (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL5846986 0.80 TSHR (0.50) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2291745 0.77 CYP1A2 (0.58) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7650795 0.77 CYP1A2 (0.58) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL22062056 0.76 RAB9A (0.49) ALDH1A1HSD17B10CYP3A4HPGDTSHR
SCHEMBL28496032 0.75 CYP1A2 (0.56) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10678156-B2 Pigment dispersion, method for manufacturing toner, aqueous ink, and triazo compound CANON KABUSHIKI KAISHA (JP) 2020-06-09 US disclosed