Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572609 | 1.00 | TSHR (0.52) | TSHRCYP1A1CYP1B1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5846986 | 0.98 | TSHR (0.50) | TSHRCYP1A1CYP1B1TDP1ALDH1A1 | |
| SCHEMBL22062056 | 0.86 | RAB9A (0.49) | TSHRCYP1A1CYP1B1TDP1ALDH1A1 | |
| SCHEMBL22062012 | 0.81 | SIGMAR1 (0.50) | TSHRTDP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL4908899 | 0.81 | SIGMAR1 (0.50) | TSHRTDP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL3329718 | 0.80 | POLB (0.51) | TSHRTDP1ALDH1A1HSD17B10HPGD | |
| SCHEMBL11591356 | 0.80 | MEN1 (0.61) | ALDH1A1CYP3A4NPC1RAB9ACYP1A2 | |
| SCHEMBL11591353 | 0.80 | MEN1 (0.61) | ALDH1A1CYP3A4NPC1RAB9ACYP1A2 | |
| SCHEMBL8701015 | 0.80 | THRB (0.49) | TSHRCYP1A1CYP1B1TDP1HSD17B10 | |
| SCHEMBL8701010 | 0.80 | THRB (0.49) | TSHRCYP1A1CYP1B1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475287-B1 | COMPOUNDS, LINKED WITH HAPTENS, FOR THE DETECTION OF SENESCENT CELLS | UNIV MANCHESTER (GB) | 2022-03-30 | — | — | EP | disclosed |
| EP-3475265-B1 | COMPOUNDS FOR THE DETECTION OF SENESCENT CELLS | UNIV MANCHESTER (GB) | 2021-06-16 | — | — | EP | disclosed |
| US-11034839-B2 | Compounds, linked with haptens, for the detection of senescent cells | THE UNIVERSITY OF MANCHESTER (GB) | 2021-06-15 | — | — | US | disclosed |
| US-10947390-B2 | Compounds for the detection of senescent cells | THE UNIVERSITY OF MANCHESTER (GB) | 2021-03-16 | — | — | US | disclosed |
| US-20210009911-A1 | PROCESSING BIOMASS | XYLECO INC (US) | 2021-01-14 | — | — | US | disclosed |
| US-10597595-B2 | Processing biomass | XYLECO, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| US-20190315966-A1 | COMPOUNDS FOR THE DETECTION OF SENESCENT CELLS | THE UNIVERSITY OF MANCHESTER (GB) | 2019-10-17 | — | — | US | disclosed |
| EP-2091322-B1 | CLUMP RECOGNITION ANIMAL LITTER | CHURCH & DWIGHT CO INC (US) | 2019-08-14 | — | — | EP | disclosed |
| US-20190233751-A1 | PROCESSING BIOMASS | XYLECO, INC. | 2019-08-01 | — | — | US | disclosed |
| US-20190225812-A1 | COMPOUNDS, LINKED WITH HAPTENS, FOR THE DETECTION OF SENESCENT CELLS | THE UNIVERSITY OF MANCHESTER (GB) | 2019-07-25 | — | — | US | disclosed |
| CN-1081100-A | The dentifrice composition that contains silicon dioxide that can be compatible with organic amine compound | RHONE POULENC CHIMIE (FR) | 1994-01-26 | — | — | CN | disclosed |
| EP-0545318-A1 | Process for preparing alkylene sulfides | NIPPON SHOKUBAI CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| CN-1047066-A | Silica for toothpaste composition compatible with organic amine compound | RHONE POULENC CHIMIE (FR) | 1990-11-21 | — | — | CN | disclosed |
| EP-0396459-A1 | Silica for dentifrice compositions which is compatible with organic amino-compounds | RHONE-POULENC CHIMIE (FR) | 1990-11-07 | — | — | EP | disclosed |
| EP-0370795-A2 | Method of producing aziridine compounds | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4842646-A | CONTAINING HYDROXYCARBOXYLIC ACID | SARANDA CONSOLIDATED LIMITED PARTNERSHIP (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0315503-A1 | Silica for dentifrice compositions, compatible more particularly with chlorhexidine | RHONE-POULENC CHIMIE (FR) | 1989-05-10 | — | — | EP | disclosed |
| EP-0261637-A2 | Substantive dyes, inks and dye baths | Gamblin, Rodger L. (US) | 1988-03-30 | — | — | EP | disclosed |
| US-4707545-A | Process for the preparation of lithium salts of anionic dyes by reacting the calcium salts with lithium sulfate or lithium hydrogen sulfate | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-17 | — | — | US | disclosed |
| US-3989706-A | CONTACTING A HYDROCARBON, AMMONIA AND OXYGEN WITH A SOLID ACID CATALYST | TEIJIN LIMITED (JA) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225812-A1 | COMPOUNDS, LINKED WITH HAPTENS, FOR THE DETECTION OF SENESCENT CELLS | CCNB1, LMNB1, S100B | TSHR 2650/4885CYP1A1 1173/4885CYP1B1 338/4885 |
| US-11034839-B2 | Compounds, linked with haptens, for the detection of senescent cells | CCNB1, LMNB1, S100B | TSHR 2650/4885CYP1A1 1173/4885CYP1B1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.