SCHEMBL22062741

SCHEMBL22062741

c1ccc2cc3c(cc2c1)nc1n3c2cccc3c2n1c1nc2ccccc2n31

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.40
ALDH1A1 P00352 7/20 0.40
LMNA P02545 4/20 0.40
NQO2 P16083 1/20 0.38
SMN1; SMN2 Q16637 5/20 0.37
HPGD P15428 5/20 0.37
IKBKB O14920 1/20 0.37
CHUK O15111 1/20 0.37
HSD17B10 Q99714 5/20 0.35
MAPT P10636 4/20 0.35
TP53 P04637 3/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
GAA P10253 2/20 0.35
PKM P14618 2/20 0.35
CSNK1A1 P48729 1/20 0.34
CLK2 P49760 1/20 0.34
LIMK1 P53667 1/20 0.34
DYRK1A Q13627 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22063137 0.95 KDM4E (0.43) KDM4EALDH1A1LMNANQO2SMN1; SMN2
SCHEMBL22062740 0.88 KDM4E (0.41) KDM4EALDH1A1LMNASMN1; SMN2HPGD
SCHEMBL22063251 0.83 KDM4E (0.36) KDM4EALDH1A1LMNAHPGDIKBKB
SCHEMBL22063141 0.82 KDM4E (0.34) KDM4EALDH1A1LMNAIKBKBCHUK
SCHEMBL22063142 0.82 KDM4E (0.34) KDM4EALDH1A1LMNAIKBKBCHUK
SCHEMBL22063131 0.81 ALDH1A1 (0.40) KDM4EALDH1A1LMNANQO2SMN1; SMN2
SCHEMBL13852950 0.80 ALDH1A1 (0.52) KDM4EALDH1A1LMNANQO2SMN1; SMN2
SCHEMBL22088706 0.80 KDM4E (0.38) KDM4EALDH1A1LMNASMN1; SMN2HPGD
SCHEMBL22087428 0.80 KDM4E (0.37) KDM4EALDH1A1LMNANQO2SMN1; SMN2
SCHEMBL22062558 0.79 KDM4E (0.39) KDM4EALDH1A1LMNANQO2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EMC2, NFE2L2, AOC2 KDM4E 1152/4885ALDH1A1 1970/4885LMNA 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.