Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18695272 | 0.76 | TP53 (0.45) | TP53L3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL20745023 | 0.74 | KDM4E (0.42) | KDM4EPOLBPTGS1PTGS2CYP3A4 | |
| SCHEMBL18695216 | 0.74 | TP53 (0.42) | TP53L3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL20763116 | 0.73 | CNR1 (0.35) | — | |
| SCHEMBL18695205 | 0.70 | TP53 (0.41) | TP53L3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL27209645 | 0.69 | LMNA (0.40) | TP53L3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL2933232 | 0.67 | GRN (0.61) | KDM4EGAA | |
| SCHEMBL12455966 | 0.67 | GRN (0.47) | KDM4EGAA | |
| SCHEMBL22637870 | 0.67 | TP53 (0.50) | TP53L3MBTL1LMNAKDM4EPOLB | |
| SCHEMBL20763628 | 0.64 | KDM4E (0.45) | KDM4EPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11589586-B2 | Pesticidal and parasiticidal pyrazole-isoxazoline compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-02-28 | — | — | US | disclosed |
| US-20200178531-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11589586-B2 | Pesticidal and parasiticidal pyrazole-isoxazoline compounds | PRDX1, PRDX5, P2RX7 | TP53 4282/4885L3MBTL1 2376/4885LMNA 2425/4885 |
| US-20200178531-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | PRDX1, PRDX5, P2RX7 | TP53 4282/4885L3MBTL1 2376/4885LMNA 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.