Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22067596 | 0.73 | TP53 (0.40) | — | |
| SCHEMBL31459445 | 0.64 | KDM4E (0.48) | CNR1CNR2PKM | |
| SCHEMBL23224118 | 0.63 | CNR1 (0.46) | CNR1CNR2PKM | |
| SCHEMBL10203515 | 0.63 | CNR1 (0.46) | CNR1CNR2PKM | |
| SCHEMBL18695216 | 0.62 | TP53 (0.42) | — | |
| SCHEMBL6527928 | 0.62 | CNR1 (0.45) | CNR1CNR2PKM | |
| SCHEMBL31459470 | 0.60 | ALDH1A1 (0.42) | CNR1CNR2PKM | |
| SCHEMBL19795734 | 0.58 | CNR1 (0.40) | CNR1CNR2PKM | |
| SCHEMBL28999256 | 0.57 | DGAT1 (0.40) | PKM | |
| SCHEMBL23212928 | 0.57 | TP53 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11589586-B2 | Pesticidal and parasiticidal pyrazole-isoxazoline compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-02-28 | — | — | US | disclosed |
| EP-3668866-B1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2023-01-18 | — | — | EP | disclosed |
| US-20200178531-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-06-11 | — | — | US | disclosed |
| WO-2019036407-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | MERIAL, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11589586-B2 | Pesticidal and parasiticidal pyrazole-isoxazoline compounds | PRDX1, PRDX5, P2RX7 | CNR1 1817/4885CNR2 2383/4885PKM 413/4885 |
| US-20200178531-A1 | PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS | PRDX1, PRDX5, P2RX7 | CNR1 1817/4885CNR2 2383/4885PKM 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.