Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098850 | 0.89 | HPGD (0.63) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL22069578 | 0.89 | HPGD (0.63) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL22069631 | 0.87 | HSPB1 (0.57) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL11511746 | 0.87 | PDE7A (0.71) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL11092189 | 0.84 | VCAM1 (0.57) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL6918825 | 0.81 | HSPB1 (0.53) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL31447962 | 0.81 | HSPB1 (0.53) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL4031207 | 0.81 | KMT2A (0.58) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL6237528 | 0.81 | KMT2A (0.65) | KMT2AMEN1PDE7AMAPTHPGD | |
| SCHEMBL4965383 | 0.81 | PDE7A (0.63) | KMT2AMEN1PDE7AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |