Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.53 |
| ▸ | ESRRA | P11474 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962765 | 0.86 | MAPT (0.56) | KMT2AMEN1PDE7AESRRAMAPT | |
| SCHEMBL22069578 | 0.85 | HPGD (0.63) | KMT2AMEN1PDE7AMAPTLMNA | |
| SCHEMBL30098850 | 0.85 | HPGD (0.63) | KMT2AMEN1PDE7AMAPTLMNA | |
| SCHEMBL11026917 | 0.84 | ALOX5 (0.54) | KMT2AMEN1ESRRAALOX5MAPT | |
| SCHEMBL27713193 | 0.84 | HSPB1 (0.66) | KMT2AMEN1ALOX5MAPTLMNA | |
| SCHEMBL11511746 | 0.83 | PDE7A (0.71) | KMT2AMEN1PDE7AMAPTLMNA | |
| SCHEMBL10965789 | 0.83 | MAPT (0.61) | KMT2AMEN1PDE7AMAPTLMNA | |
| SCHEMBL11030748 | 0.83 | ALOX5 (0.52) | KMT2AMEN1ALOX5MAPTLMNA | |
| SCHEMBL22069554 | 0.81 | KMT2A (0.62) | KMT2AMEN1PDE7AMAPTLMNA | |
| SCHEMBL3484735 | 0.81 | KMT2A (0.69) | KMT2AMEN1PDE7AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |
| EP-0081743-B1 | NAPHTHOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1986-05-14 | — | — | EP | disclosed |
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0081743-A2 | Naphthoxyphenyl ureas, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0013414-B1 | UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | CELAMERCK GmbH & Co. KG (DE) | 1982-06-23 | — | — | EP | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4275077-A | Insecticidal acyl urea derivatives | CELAMERCK GMBH & CO. KG (DE) | 1981-06-23 | — | — | US | disclosed |
| EP-0013414-A2 | Urea derivatives, process for their preparation and their use as insecticides | CELAMERCK GmbH & Co. KG (DE) | 1980-07-23 | — | — | EP | disclosed |