SCHEMBL2207002

SCHEMBL2207002

Nc1c(N)c2c(c(-c3ccccc3)c1-c1ccccc1)-c1c-2c(O)c(O)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.38
PDE4B Q07343 2/20 0.38
PDE4C Q08493 2/20 0.38
PDE4D Q08499 2/20 0.38
MAPT P10636 3/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HSP90AA1 P07900 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6678522 0.92 PDE4A (0.38) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL223699 0.87 PDE4A (0.41) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL21248552 0.82 PDE4A (0.43) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL8644874 0.82 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL2069055 0.82 HSD17B10 (0.48) MAPTLMNAHTTHSD17B10KDM4E
SCHEMBL19253312 0.79 HDAC4 (0.52) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL19253225 0.79 HSD17B10 (0.46) MAPTLMNAHTTHSD17B10KDM4E
SCHEMBL6678528 0.79 PDE4B (0.35) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL14353864 0.77 PDE4B (0.50) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL5030574 0.77 HSD17B10 (0.48) MAPTLMNAHTTHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8013074-B2 Bulk low conversion polymerization of styrene and butylacrylate; combining with maleic anhydride and aqueous emulsion polymerizing to form particles; combining with amine compound XEROX CORPORATION (US) 2011-09-06 US claimed
US-7981973-B2 Bulk low conversion polymerization of styrene and butylacrylate; combining with maleic anhydride and aqueous emulsion polymerizing to form particles; combining with amine compound XEROX CORPORATION (US) 2011-07-19 US claimed
US-7615327-B2 Bulk low conversion polymerization of styrene and butylacrylate; combining with maleic anhydride and aqueous emulsion polymerizing to form poly(styrene/maleic anhydride-b-styrene/butylacrylate particles; combining with amine compound; first and second heating XEROX CORPORATION (US) 2009-11-10 US claimed
US-20080199802-A1 TONER PROCESS XEROX CORPORATION (US) 2008-08-21 US claimed
US-7244485-B2 endless flexible seamed belt having a puzzle cut seam, wherein the seam comprises an adhesive comprising a polyamide and optionally, an electrically conductive filler XEROX CORPORATION (US) 2007-07-17 US claimed
US-20060222805-A1 Imageable seamed belts having polyamide adhesive between interlocking seaming members XEROX CORPORATION. 2006-10-05 US claimed
US-20060105261-A1 Toner process XEROX CORPORATION 2006-05-18 US claimed
EP-1251157-B1 Use of an adhesive comprising polyamide and electrically conductive filler for electrostatographic apparatuses XEROX CORP (US) 2004-11-17 EP claimed
US-6761978-B2 FOR USE IN BONDING COMPONENTS OF ELECTROSTATOGRAPHIC, CONTACT ELECTROSTATIC, DIGITAL PRINTING MACHINES XEROX CORPORATION 2004-07-13 US claimed
US-6602156-B2 Imageable seamed belts having polyamide and doped metal oxide adhesive between interlocking seaming members XEROX CORPORATION 2003-08-05 US claimed
US-20030113501-A1 Plasticizer other than bis(dihydroxydiethylamino)triphenyl methane, bis(diethylamino)triphenyl methane, or dihydroxy tetraphenylbiphenylenediamine; use in electrostatographic, contact electrostatic, digital and other machines. XEROX CORPORATION 2003-06-19 US claimed
EP-1319864-A2 Imageable seamed belts having improved adhesive with plasticizer between interlocking seaming members Xerox Corporation (US) 2003-06-18 EP claimed
US-20030109344-A1 Electrostatographic digital printer; seam invisible to the xerographic imaging process; flexibility, high strength, noncracking XEROX CORPORATION 2003-06-12 US claimed
US-20030015690-A1 Process for forming a mixed solvent adhesive solution XEROX CORPORATION 2003-01-23 US claimed
US-20020177645-A1 Polyamide and conductive filler adhesive XEROX CORPORATION 2002-11-28 US claimed
EP-1251157-A1 Polyamide and conductive filler adhesive Xerox Corporation (US) 2002-10-23 EP claimed
US-20020150408-A1 Imageable seamed belts having polyamide adhesive between interlocking seaming members XEROX CORPORATION 2002-10-17 US claimed
EP-1249638-B1 Imageable seamed belts having polyamide adhesive between interlocking seaming members XEROX CORP (US) 2017-04-05 EP disclosed
US-20020150408-A1 Imageable seamed belts having polyamide adhesive between interlocking seaming members XEROX CORPORATION 2002-10-17 US disclosed
EP-1249638-A2 Imageable seamed belts having polyamide adhesive between interlocking seaming members Xerox Corporation (US) 2002-10-16 EP disclosed