Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675595 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HSD17B10MAPTLMNAHPGD | |
| SCHEMBL1754108 | 0.87 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL223699 | 0.86 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL5030574 | 0.84 | HSD17B10 (0.48) | ALDH1A1HSD17B10MAPTLMNAHPGD | |
| SCHEMBL14353864 | 0.84 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL2207002 | 0.82 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL1899394 | 0.81 | HSD17B10 (0.46) | ALDH1A1HSD17B10MAPTLMNAHPGD | |
| SCHEMBL454643 | 0.81 | PDE4B (0.54) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL29001722 | 0.81 | PDE4B (0.58) | PDE4APDE4BPDE4CPDE4DHDAC4 | |
| SCHEMBL28535205 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HSD17B10MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749674-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-12-16 | — | — | EP | claimed |
| US-20200369697-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-11-26 | — | — | US | claimed |
| WO-2019157376-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-08-15 | — | — | WO | claimed |
| US-11702436-B2 | Tetraphenylphenoxy tungsten oxo alkylidene complexes and methods of making same and use thereof | VERBIO VEREINIGTE BIOENERGIE AG (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11702436-B2 | Tetraphenylphenoxy tungsten oxo alkylidene complexes and methods of making same and use thereof | VERBIO VEREINIGTE BIOENERGIE AG (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11702436-B2 | Tetraphenylphenoxy tungsten oxo alkylidene complexes and methods of making same and use thereof | VERBIO VEREINIGTE BIOENERGIE AG (DE) | 2023-07-18 | — | — | US | disclosed |
| EP-3768691-A1 | TETRAPHENYLPHENOXY TUNGSTEN OXO ALKYLIDENE COMPLEXES, METHODS OF MAKING SAME AND USE THEREOF | Verbio Vereinigte BioEnergie AG (DE) | 2021-01-27 | — | — | EP | disclosed |
| US-20210017207-A1 | TETRAPHENYLPHENOXY TUNGSTEN OXO ALKYLIDENE COMPLEXES AND METHODS OF MAKING SAME AND USE THEREOF | VERBIO SE (DE) | 2021-01-21 | — | — | US | disclosed |
| US-20210017207-A1 | TETRAPHENYLPHENOXY TUNGSTEN OXO ALKYLIDENE COMPLEXES AND METHODS OF MAKING SAME AND USE THEREOF | VERBIO SE (DE) | 2021-01-21 | — | — | US | disclosed |
| US-20200369697-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-11-26 | — | — | US | disclosed |
| WO-2019180230-A1 | TETRAPHENYLPHENOXY TUNGSTEN OXO ALKYLIDENE COMPLEXES, METHODS OF MAKING SAME AND USE THEREOF | XIMO AG (CH) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369697-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MSRB3, MMAB, CYB5R3 | PDE4A 3748/4885PDE4B 3559/4885PDE4C 3496/4885 |
| US-20210017207-A1 | TETRAPHENYLPHENOXY TUNGSTEN OXO ALKYLIDENE COMPLEXES AND METHODS OF MAKING SAME AND USE THEREOF | PPOX, PPIP5K2, AOC1 | PDE4A 4615/4885PDE4B 4761/4885PDE4C 4581/4885 |
| US-11702436-B2 | Tetraphenylphenoxy tungsten oxo alkylidene complexes and methods of making same and use thereof | PPOX, PPIP5K2, AOC1 | PDE4A 4615/4885PDE4B 4761/4885PDE4C 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.