Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30129663 | 0.73 | SPAST (1.00) | SPASTIGF1R | |
| SCHEMBL22035095 | 0.73 | SPAST (1.00) | SPASTIGF1R | |
| SCHEMBL22035098 | 0.73 | SPAST (1.00) | SPASTIGF1R | |
| SCHEMBL22034758 | 0.65 | SPAST (0.74) | SPASTIGF1R | |
| SCHEMBL22034761 | 0.65 | SPAST (0.74) | SPASTIGF1R | |
| SCHEMBL22034762 | 0.60 | SPAST (0.54) | SPASTIGF1R | |
| SCHEMBL22035048 | 0.54 | SPAST (1.00) | SPASTIGF1R | |
| SCHEMBL22035049 | 0.54 | SPAST (1.00) | SPASTIGF1R | |
| SCHEMBL22072083 | 0.53 | SPAST (0.61) | SPASTIGF1R | |
| SCHEMBL7028703 | 0.52 | AURKA (0.72) | SPAST |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020118183-A1 | 2,4-DIAMINOPYRIMIDINE BICYCLES FOR TREATING CANCER | KAPOOR TARUN M (US) | 2020-06-11 | — | — | WO | disclosed |