Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24266787 | 0.88 | EYA3 (0.36) | CYP2C19EYA3SLC22A12TSHRTHRA | |
| SCHEMBL24267353 | 0.79 | ALDH1A1 (0.39) | CYP2C19EYA3SLC22A12TSHRHTT | |
| SCHEMBL24266348 | 0.79 | KDR (0.32) | EYA3THRATHRB | |
| SCHEMBL22072500 | 0.79 | EYA3 (0.58) | CYP2C19EYA3SLC22A12TSHRTHRB | |
| SCHEMBL22072522 | 0.76 | EYA3 (0.45) | CYP2C19EYA3SLC22A12TSHRTHRB | |
| SCHEMBL25719653 | 0.76 | EYA3 (0.34) | EYA3SLC22A12THRATHRB | |
| SCHEMBL24267018 | 0.74 | EYA3 (0.36) | CYP2C19EYA3SLC22A12TTR | |
| SCHEMBL24103740 | 0.71 | CYP2C19 (0.32) | CYP2C19EYA3 | |
| SCHEMBL26211957 | 0.68 | EYA3 (0.42) | CYP2C19EYA3SLC22A12TSHRTHRB | |
| SCHEMBL22072519 | 0.68 | TTR (0.46) | CYP2C19EYA3SLC22A12TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957629-B1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | ARTHROSI THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |