SCHEMBL2207338

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8972231	0.80	GABRP (0.41)	KDM4EALDH1A1HCAR2GABRPGABRD
	SCHEMBL2724263	0.75	HTT (0.45)	AKR1C3AKR1C2AKR1C1AKR1C4KDM4E
	SCHEMBL1141287	0.72	MEN1 (0.42)	KDM4EALDH1A1POLBHTTOPRK1
	SCHEMBL741418	0.72	HTT (0.55)	KDM4EALDH1A1POLBGABRA1GABRG2
	SCHEMBL3249138	0.71	ALDH1A1 (0.58)	KDM4EALDH1A1TSHRSMN1; SMN2
	SCHEMBL429271	0.71	AKR1C3 (0.48)	AKR1C3AKR1C2AKR1C1AKR1C4KDM4E
	Hydrochloric Acid SCHEMBL11567115	0.70	ALDH1A1 (0.57)	KDM4EALDH1A1TSHRSMN1; SMN2
	SCHEMBL732403	0.70	DHODH (0.44)	AKR1C3AKR1C2AKR1C1AKR1C4KDM4E
	SCHEMBL4904323	0.69	AKR1C3 (0.36)	AKR1C3AKR1C2AKR1C1AKR1C4KDM4E
	SCHEMBL1505655	0.69	KDM4E (0.45)	AKR1C3AKR1C2AKR1C1AKR1C4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.