Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741418 | 0.87 | HTT (0.55) | HTTTSHRKDM4EGLAMEN1 | |
| SCHEMBL27903036 | 0.83 | CA12 (0.44) | HTTTSHRKDM4EMEN1KMT2A | |
| SCHEMBL25311292 | 0.83 | DHODH (0.43) | HTTTSHREGFRERBB2KDM4E | |
| SCHEMBL27920761 | 0.82 | TSHR (0.56) | HTTTSHREGFRERBB2KDM4E | |
| Hydrochloric Acid SCHEMBL25311682 | 0.81 | DHODH (0.42) | HTTTSHREGFRERBB2KDM4E | |
| SCHEMBL1617941 | 0.81 | HSD17B10 (0.41) | HTTTSHRKDM4EMEN1KMT2A | |
| SCHEMBL1610495 | 0.81 | CYP1A2 (0.49) | HTTTSHREGFRKDM4EMEN1 | |
| SCHEMBL5767408 | 0.81 | KEAP1 (0.42) | HTTTSHRKDM4EMEN1KMT2A | |
| SCHEMBL30592903 | 0.81 | CYP1A2 (0.49) | HTTTSHREGFRKDM4EMEN1 | |
| SCHEMBL5766222 | 0.81 | ALDH1A1 (0.47) | HTTTSHRKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103113298-A | Preparation method of 7-bromo-4-hydroxy-3-quinoline carboxylic acid | BEIJING GREENCHEM TECHNOLOGY CO LTD | 2013-05-22 | — | — | CN | claimed |
| CN-116478130-B | N-hydroxyquinoline carboxamide compounds and uses thereof | 深圳默元生物科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| WO-2023138674-A1 | N-HYDROXYQUINOLINE CARBOXAMIDE COMPOUND AND USE THEREOF | 默达药物（香港）有限公司 | 2023-07-27 | — | — | WO | disclosed |
| CN-116478130-A | N-hydroxyquinoline carboxamide compounds and uses thereof | 深圳默元生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-103113298-B | Preparation method of 7-bromo-4-hydroxy-3-quinoline carboxylic acid | BEIJING GREENCHEM TECHNOLOGY CO LTD | 2014-12-31 | — | — | CN | disclosed |
| CN-103113298-B | Preparation method of 7-bromo-4-hydroxy-3-quinoline carboxylic acid | BEIJING GREENCHEM TECHNOLOGY CO LTD | 2014-12-31 | — | — | CN | disclosed |
| CN-103113298-B | Preparation method of 7-bromo-4-hydroxy-3-quinoline carboxylic acid | BEIJING GREENCHEM TECHNOLOGY CO LTD | 2014-12-31 | — | — | CN | disclosed |
| EP-2635279-A2 | CHEMICAL COMPOUNDS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-11 | — | — | EP | disclosed |
| US-20130225524-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2013-08-29 | — | — | US | disclosed |
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |
| CN-103113298-A | Preparation method of 7-bromo-4-hydroxy-3-quinoline carboxylic acid | BEIJING GREENCHEM TECHNOLOGY CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-103113298-A | Preparation method of 7-bromo-4-hydroxy-3-quinoline carboxylic acid | BEIJING GREENCHEM TECHNOLOGY CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-103113298-A | Preparation method of 7-bromo-4-hydroxy-3-quinoline carboxylic acid | BEIJING GREENCHEM TECHNOLOGY CO LTD | 2013-05-22 | — | — | CN | disclosed |
| WO-2012061557-A2 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225524-A1 | Chemical Compounds | LDHA, NQO2, LDHB | HTT 3157/4885TSHR 3703/4885EGFR 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.