Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 16/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772855 | 0.85 | TRPM8 (0.76) | TRPM8NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29779963 | 0.85 | TRPM8 (0.76) | TRPM8NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13471440 | 0.85 | TRPM8 (1.00) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL20773411 | 0.84 | TRPM8 (0.55) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL22074356 | 0.83 | TRPM8 (0.67) | TRPM8NPC1SMN1; SMN2 | |
| SCHEMBL29779986 | 0.82 | TRPM8 (0.76) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL20773022 | 0.82 | TRPM8 (0.76) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL22074394 | 0.81 | TRPM8 (0.57) | TRPM8SMN1; SMN2HPGD | |
| SCHEMBL22074441 | 0.80 | ALDH1A1 (0.56) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29780002 | 0.80 | ALDH1A1 (0.56) | TRPM8NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675809-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| EP-3675809-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | BASF SE (DE) | 2022-09-06 | — | — | US | disclosed |
| EP-3675809-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-06-18 | — | — | US | disclosed |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | TRPM8, TRPM7, TRPM5 | TRPM8 1/4885NPC1 708/4885RAB9A 3290/4885 |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM5 | TRPM8 1/4885NPC1 708/4885RAB9A 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.