Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 15/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20773022 | 1.00 | TRPM8 (0.76) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13471440 | 0.86 | TRPM8 (1.00) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL22074331 | 0.84 | TRPM8 (0.67) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL22074404 | 0.82 | TRPM8 (0.74) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30579664 | 0.81 | TRPM8 (0.57) | TRPM8SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL20777249 | 0.81 | TRPM8 (0.57) | TRPM8SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL20773148 | 0.80 | ALDH1A1 (0.55) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL31352627 | 0.80 | TRPM8 (0.67) | TRPM8NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL20772858 | 0.79 | TRPM8 (0.72) | TRPM8MAPTKDM4EALDH1A1MAOB | |
| SCHEMBL29779962 | 0.79 | TRPM8 (0.72) | TRPM8MAPTKDM4EALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | BASF SE (DE) | 2022-09-06 | — | — | US | claimed |
| EP-3675809-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | TRPM8, TRPM7, TRPM5 | TRPM8 1/4885NPC1 708/4885RAB9A 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.