Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.47 |
| ▸ | ADH5 | P11766 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HAT1 | O14929 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22078068 | 0.89 | TBXAS1 (0.50) | TBXAS1ADH5CYP2C19HAT1EP300 | |
| SCHEMBL22077233 | 0.89 | ADH5 (0.61) | TBXAS1ADH5CYP2C19HAT1EP300 | |
| SCHEMBL22076963 | 0.89 | TBXAS1 (0.49) | TBXAS1ADH5CYP2C19PLA2G4A | |
| SCHEMBL22078066 | 0.86 | USP14 (0.49) | TBXAS1HAT1EP300PLA2G10PLA2G4A | |
| SCHEMBL22078067 | 0.86 | TBXAS1 (0.47) | TBXAS1PLA2G4AMAPTMAOB | |
| SCHEMBL25492032 | 0.85 | HAT1 (0.41) | TBXAS1ADH5CYP2C19HAT1EP300 | |
| SCHEMBL20535801 | 0.85 | ADH5 (0.49) | ADH5CYP2C19HAT1EP300CYP3A4 | |
| SCHEMBL30772942 | 0.85 | ADH5 (0.49) | ADH5CYP2C19HAT1EP300CYP3A4 | |
| SCHEMBL30927852 | 0.85 | ADH5 (0.49) | ADH5CYP2C19HAT1EP300CYP3A4 | |
| SCHEMBL22078076 | 0.82 | TBXAS1 (0.53) | TBXAS1ADH5CYP2C19PLA2G4ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS, INC. | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSR, CBR3, CBR1 | TBXAS1 1031/4885ADH5 93/4885CYP2C19 17/4885 |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSR, CBR3, CBR1 | TBXAS1 1031/4885ADH5 93/4885CYP2C19 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.