Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 5/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | HAT1 | O14929 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076995 | 0.89 | TBXAS1 (0.47) | ADH5CYP2C19TBXAS1PLA2G10HAT1 | |
| SCHEMBL25492037 | 0.87 | ADH5 (0.48) | ADH5CYP2C19TBXAS1HAT1EP300 | |
| SCHEMBL20535798 | 0.87 | ADH5 (0.54) | ADH5CYP2C19TBXAS1PDE4APDE4B | |
| SCHEMBL30772955 | 0.87 | ADH5 (0.54) | ADH5CYP2C19TBXAS1PDE4APDE4B | |
| SCHEMBL22076978 | 0.87 | ADH5 (0.45) | ADH5CYP2C19TBXAS1PLA2G10PLA2G4A | |
| SCHEMBL25493548 | 0.87 | ADH5 (0.45) | ADH5CYP2C19TBXAS1PLA2G10PLA2G4A | |
| SCHEMBL22076992 | 0.86 | USP14 (0.44) | ADH5CYP2C19TBXAS1PLA2G10HAT1 | |
| SCHEMBL30772954 | 0.82 | ADH5 (0.56) | ADH5CYP2C19TBXAS1PDE4APDE4B | |
| SCHEMBL20535770 | 0.82 | ADH5 (0.56) | ADH5CYP2C19TBXAS1PDE4APDE4B | |
| SCHEMBL22078068 | 0.80 | TBXAS1 (0.50) | ADH5CYP2C19TBXAS1HAT1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS, INC. | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSR, CBR3, CBR1 | ADH5 93/4885CYP2C19 17/4885TBXAS1 1031/4885 |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSR, CBR3, CBR1 | ADH5 93/4885CYP2C19 17/4885TBXAS1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.