Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764844 | 0.85 | SMN1; SMN2 (0.50) | KMT2ANPC1HTTSMN1; SMN2HSD17B1 | |
| SCHEMBL5709905 | 0.81 | KMT2A (0.53) | KMT2ANPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL29499836 | 0.81 | KMT2A (0.53) | KMT2ANPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31369141 | 0.79 | LMNA (0.50) | KMT2ANPC1HTTSMN1; SMN2MEN1 | |
| SCHEMBL286054 | 0.79 | LMNA (0.50) | KMT2ANPC1HTTSMN1; SMN2MEN1 | |
| SCHEMBL13557813 | 0.78 | ALDH1A1 (0.57) | KMT2ANPC1HTTSMN1; SMN2MEN1 | |
| SCHEMBL9544691 | 0.77 | HTT (0.56) | KMT2ANPC1HTTSMN1; SMN2MEN1 | |
| SCHEMBL1758224 | 0.76 | HTT (0.60) | KMT2ANPC1HTTSMN1; SMN2HSD17B1 | |
| SCHEMBL30355061 | 0.76 | HTT (0.60) | KMT2ANPC1HTTSMN1; SMN2HSD17B1 | |
| SCHEMBL11019202 | 0.75 | MAPK13 (0.48) | KMT2ANPC1HTTSMN1; SMN2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3352998-B1 | USE OF AN ESTERIFIED AROMATIC POLYPHENOL DERIVATIVE FOR THE PRODUCTION OF A PHENOL-ALDEHYDE RESIN FOR REINFORCEMENT OF A RUBBER COMPOSITION | MICHELIN & CIE (FR) | 2020-06-10 | — | — | EP | disclosed |